Letrozole or Femara is one of the most admired drugs in the world of healthcare and bodybuilding. This drug has the distinction of treating infertility and formation of estrogens, which are two of the most common complications after use of harsh and aromatizable steroids. The drug is also used for treating (reversing) the spread of breast cancer (adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer) after other treatment options such as Tamoxifen therapy fail to deliver.

In the world of bodybuilding, Letrozole is admired by professional coaches and sportsmen since it can minimize the level of estrogen formation by 98 percent. This means that users do not have to bother about risks such as gynecomastia and fluid retention.

The chemical formula of this antiestrogen is C17H11N5 and its chemical name is 4,4'-(1H-1,2,4Triazol-1-ylmethylene)dibenzonitrile. Its molecular weight is 258.31 g/mol at the base; the inactive ingredient in Letrozole tablets are , microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, talc, colloidal silicon dioxide, ferric oxide, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, maize starch, and titanium dioxide.

The recommended dose of Letrozole is 2.5-3.0 mg per day and these doses can be taken with or without meals. It is important to note here that Letrozole is not meant for pregnant or pregnancy-suspecting women since its use can lead to fetal harm. Since Letrozole, at times, leads to fatigue and dizziness, it is not recommended for individuals working on heavy machines or driving or undertaking an activity that requires complete attention. When abused or of a low grade, Letrozole can lead to side effects such as headache, vomiting, constipation, nausea, and hot flashes.